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| Project Title: | General clinical research center | |
| Principal Investigators (PI): |
DEBAS HAILE T
|
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| Project Number: | 3M01RR000079-36S1 | |
| Organization: | UNIVERSITY OF CALIFORNIA SAN FRANCISCO | |
| Project Description: | ||
|---|---|---|
| With this renewal, the UCSF General Clinical Research Center begins its 30th year. Our Center is nutritionally focused, supporting a large variety of diet-controlled protocols that result in a high occupancy rate for both inpatient and outpatient studies. Our program is highly diverse by virtue of the variety of nutritional areas supported (carbohydrate, lipid, mineral, acid-base, electrolyte, vitamin D metabolism) and the variety of protocols supported in non-nutritional areas (cardiovascular pharmacology, psychopharmacology, AIDS treatment, allergy, reproductive endocrinology). During the past 5-year grant period, nearly 100 articles resulting from UCSF GCRC studies by 19 different Principal Investigators appeared in print. During the next 5-year period, 17 different Principal Investigators will study: progesterone antagonism of estrogen regulated bone mineral metabolism; circadian rhythms function in elderly; effects of growth hormone and testosterone on vitamin D metabolism in elderly; lipoprotein turnover; psychopharmacology of drug abuse; drug regimens to reverse coronary atherosclerosis; dietary and pharmacological effects on the speciation of high density lipoproteins; effect of prostaglandin inhibition by nonsteroidal anti-inflammatory drugs on bone loss during bed rest in older women; studies of lipoprotein structure in hypo-and hyperlipoproteinemia; diet potassium and hypertension in blacks and elderly; regulation of calcitriol metabolism in health and disease; the effects of aging on calcium blocker kinetics/dynamics; effect of prolonged dietary base supplementation on bone mass in postmenopausal women; effect of age on acid-base homeostasis in normal humans; prophylaxis of Pneumocystis carinii pneumonia in AIDS; dietary cholesterol effects on plasma lipoproteins; postprandial lipid metabolism in coronary artery disease; lipoprotein lipase and hepatic lipase activities in normal and hypertriglyceridemic individuals; neuromediators of allergic rhinopharyngitis; receptor-defective low density lipoproteins; the effect of sulfonylureas on pancreatic beta cell sensitivity; the effect of aging on cardiac R-R variability; noninvasive determination of autonomic regulation of heart rate and AV conduction; effect of anion accompanying diet potassium in treating patients with essential hypertension. By our current projection for the next 5-years, two or more protocols will be devoted to each of the following disorders; hypertension, atherosclerosis, aging, osteoporosis, diabetes mellitus, and AIDS. | ||
| Project Terms: | ||
| There are no related terms in database. | ||
| Project Title: | General clinical research center | |
| Principal Investigators (PI): |
DEBAS HAILE T
|
|
| Project Number: | 3M01RR000079-36S1 | |
| Organization: | UNIVERSITY OF CALIFORNIA SAN FRANCISCO | |
| Project Categories: | ||
|---|---|---|
|
• Natural Sciences > Metabolism & Nutrition > Dietology |
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| Other Information: | ||
| Fiscal Year: | 1974 | |
| Project Start Date: | 1 December 1974 | |
| Project End Date: | 30 November 1999 | Administering Institute Or Center: | NCRR |
| Project Funding Information: | ||
| Total Funding: | $2,320,154 | |
| Year | Funding Organization | Total Funding, $ |
|---|---|---|
| 1999 | NATIONAL CENTER FOR RESEARCH RESOURCES | $2,320,154 |
| Project Title: | General clinical research center | ||
| Principal Investigators (PI): |
DEBAS HAILE T
|
||
| Project Number: | 3M01RR000079-36S1 | ||
| Organization: | UNIVERSITY OF CALIFORNIA SAN FRANCISCO | ||
| Project_number | Title | Year | FY Total Cost |
|---|---|---|---|
| There are no results for this project in database. | |||
| Project Title: | General clinical research center | ||
| Principal Investigators (PI): |
DEBAS HAILE T
|
||
| Project Number: | 3M01RR000079-36S1 | ||
| Organization: | UNIVERSITY OF CALIFORNIA SAN FRANCISCO | ||
| Project number | Project title | Principal investigator | |
|---|---|---|---|
| There are no any related projects. | |||
| Project Title: | General clinical research center | |||
| Principal Investigators (PI): |
DEBAS HAILE T
|
|||
| Project Number: | 3M01RR000079-36S1 | |||
| Organization: | UNIVERSITY OF CALIFORNIA SAN FRANCISCO | |||
| Title | Abstract | Authors | Year | Rel |
|---|---|---|---|---|
| The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men. | JAMA : the journal of the American Medical Association. 1999 May 19 281 (19) :1822-9 | Goldie, S J;Kuntz, K M;Weinstein, M C;Freedberg, K A;Welton, M L;Palefsky, J M | 1999 |
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| Anal squamous intraepithelial lesions: relation to HIV and human papillomavirus infection. | Journal of acquired immune deficiency syndromes (1999). 1999 Aug 1 21 Suppl 1 () :S42-8 | Palefsky, J M | 1999 |
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| Intrapulmonary concentrations of pyrazinamide. | Antimicrobial agents and chemotherapy.. 1999 Jun 43 (6) :1329-33 | Conte Jr, J E;Golden, J A;Duncan, S;McKenna, E;Zurlinden, E | 1999 |
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| Preliminary research on plasma oxytocin in normal cycling women: investigating emotion and interpersonal distress. | Psychiatry.. 1999 62 (2) :97-113 | Turner, R A;Altemus, M;Enos, T;Cooper, B;McGuinness, T | 1999 |
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| The apolipoprotein B R3531C mutation. Characteristics of 24 subjects from 9 kindreds. | Journal of lipid research. 1999 Feb 40 (2) :318-27 | Pullinger, C R;Gaffney, D;Gutierrez, M M;Malloy, M J;Schumaker, V N;Packard, C J;Kane, J P | 1999 |
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